Archive 2011

Haematomas treated with L-Mesitran Ointment 

Skin tears and haematomas occur frequently within the growing elderly population. Surgical management can lead to complications and bring high costs for debridement and grafting.

A conservative approach to management of type 1-3 pretibial lacerations/haematomas could be the use of L-Mesitran Ointment. Using a syringe to introduce the honey allows infiltration through the haematoma, useful in painful wounds where manual removal of the haematoma is limited. Also, no additional wound is created (eg. donor site) as would be required for a skin graft approach.

These were the results of a comparative study done by Jane Pragnell, RN and Susan Nicolson, RN of the department of plastic surgery of the Royal Victoria Infirmary in Newcastle upon Tyne. The results were presented during the Wounds UK conference in Harrogate (UK) in November.

You can read the full version here.

Hematomas tratados con L-Mesitran

Laceraciones cutáneas y hematomas se producen con frecuencia dentro de la creciente población de adultos mayores.

El tratamiento quirúrgico puede llevar a complicaciones e implicar elevados costos elevado para procedimientos de desbridamiento o injerto. Un enfoque conservador para el manejo de laceraciones/hematomas pretibiales tipo 1 – 3 podría ser el uso de L-Mesitran. Utilizando una jeringa para introducir la miel permite la infiltración a través del hematoma, útil en heridas dolorosas en las cuales la remoción manual es limitada. A su vez, no se ocasiona otro tipo de herida como por ejemplo, la de una zona donante, que sería requerida para un procedimiento de injerto de piel.

Estos fueron los resultados de un estudio comparativo realizado por Jane Pragnell, RN y Susan Nicolson, RN del departamento de cirugía plástica del hospital Royal Victoria Infirmary de Newcastle. Los resultados fueron publicados durante la conferencia de la revista Wounds UK en Harrogate (Reino Unido) en noviembre.

Puede leer la versión completa aquí.

December 12, 2011

L-Mesitran reduces equine proud flesh

In equine wound healing exuberant granulation or ‘proud flesh’ is considered a major issue by the owner and the veterinarians.

According to Alex Brander (RN) L-Mesitran contributes to shorten the inflammatory phase in wound healing, thus reducing the possibility of proud flesh formation.

The author, who has a long experience with L-Mesitran products in equine wound healing praxis, published an article on his website www.veterinairewondzorg.nl. The article furthermore provides guidelines for the clinical approach to get the optimum result when working with L-Mesitran in equine wound healing.

The full article can be read online here.

Please do not hesitate to contact us, should you have any questions about this newsletter.

L-Mesitran reduce el tejido granular excesivo en equino

En la cicatrización de heridas equinas, la formación excesiva de tejido granular es considerada un problema importante para el propietario y los veterinarios.

De acuerdo con Alex Brander (RN) L-Mesitran contribuye a la disminución de la fase inflamatoria en la cicatrización de las heridas, reduciendo así la posibilidad de formación excesiva de tejido granular.

El autor, que tiene una larga experiencia con los productos L-Mesitran para la cicatrización de heridas en equinos, publicó un artículo en su sitio web www.veterinairewondzorg.nl. El artículo, además, proporciona directrices en el enfoque clínico para obtener un resultado óptimo cuando se trabaja con L-Mesitran en la cicatrización de heridas equinas.

El artículo completo puede leerse en línea aquí.

Por favor, no dude en contactarnos, si tiene alguna pregunta acerca de esta newsletter.

December 2, 2011

L-Mesitran for burns compared with silversulphadiazine in Wound Repair & Regeneration

The renowned burn research institute in Beverwijk (NL) published its latest results on L-Mesitran. L-Mesitran Soft was compared with Flamazine, Vaseline and no treatment in an in vitro burn wound model.This model is used for the testing of topical treatments on healing and bactericidal activity against Pseudomonas aeruginosa PAO1.

The research shows that overall; the best results were obtained with L-Mesitran. It was as effective as Flamazine in eliminating P.aeruginosa, but was less detrimental to wound healing. The researchers will, at a later date, aim for a full publication, after additional data has been gathered. These first findings were published by researchers of the Dutch Burn Centres in Beverwijk and the VU university medical center in Amsterdam, The Netherlands. The abstract was published in Wound Repair & Regeneration 19(5):A72.

Please do not hesitate to contact us, should you want to receive a copy of the abstract or if you have any questions about this research.

L-Mesitran para quemaduras en comparación con sulfadiazina de plata en la regeneración y cicatrización de heridas
 
El renombrado instituto de investigación de quemaduras en Beverwijk (Holanda) publicó sus últimos resultados con L-Mesitran. L-Mesitran Soft fue comparado con Flamazine, vaselina y sin tratamiento en un modelo quemadura in vitro. Este modelo se utiliza para el análisis de tratamientos tópicos con respecto a la cicatrización y la actividad bactericida frente a Pseudomonas aeruginosa PAO1.

El estudio muestra que, en general, los mejores resultados se obtuvieron con L-Mesitran. Fue tan eficaz como Flamazine en la eliminación de P.aeruginosa, pero menos perjudicial para la cicatrización de heridas. Los investigadores, posteriormente proporcionarán una publicación completa, una vez sean recolectados datos adicionales. Estos primeros resultados fueron publicados por investigadores del Centro Holandés de quemaduras en Beverwijk y el Centro Médico Universitario en Amsterdam, Holanda.

El resumen fue publicado en: Wound Repair & Regeneration 19 (5): A72. Por favor, no dude en contactarnos, si desea recibir una copia del resumen o si tiene alguna pregunta sobre esta investigación.

November 8, 2011

Veterinary use of L-Mesitran: Tortoise, bite wound injuries treated with honey gel

On October 21st a case study about the veterinary use of L-Mesitran on a tortoise with bite wound injuries was published online in Vet-Magazin.com.

An approximately 5 year old female Hermann's tortoise was found seriously injured in a garden. It looked like a dog had played with the tortoise and had been chewing on her. At first the wound was treated with analgesia, antimicrobial agents and received in infusion with NaCl, glucose and vitamins.

Thereafter the daily L-Mesitran Soft treatment started.This treatment made sure that infections to the soft tissue and the carapace were prevented. The tortoise fully recovered from its bite injuries in only 6 weeks

The German version of this case study "Bissverletzungen bei einer Griechischen Landschildkröte" can be read online here.

You can click here for the complete English version of the case study.

Please do not hesitate to contact us, should you have any questions regarding the presented case study.

Uso veterinario de L-Mesitran: Tortuga con heridas por mordeduras tratadas con gel de miel 

El 21 de octubre fue publicado on-line en Vet-Magazin.com un estudio de caso acerca del uso veterinario de L-Mesitran en una tortuga con lesiones por mordeduras.

Una tortuga Hermann hembra de aproximadamente 5 años de edad, fue encontrada gravemente herida en un jardín. Parecía que un perro había jugado con la tortuga y la había mordido varias veces. Inicialmente la herida fue tratada con analgésicos, agentes antimicrobianos y recibió una infusión de NaCl, glucosa y vitaminas.

A partir de entonces, se inició un tratamiento diario con L-Mesitran Soft. Este tratamiento aseguró la prevención de infección de los tejidos blandos y del caparazón.La tortuga se recuperó completamente de las heridas por mordeduras en sólo 6 semanas.

La versión alemana de este estudio de caso "bei einer Bissverletzungen Griechischen Landschildkröte" se puede leer on-line aquí.

Puede hacer clic aquí para la versión completa en Inglés del estudio de caso. Por favor, no dude en contactarnos si tiene alguna pregunta relacionada con el estudio de caso presentado.

November 3, 2011

Management of diabetic foot ulceration with honey

The latest Wounds UK Journal published a case report on the use of L-Mesitran Soft in the treatment of diabetic foot ulcerations.

A 48-year-old male patient, type 1 diabetes, had sensitive, motor and autonomic diabetic neuropathy. After an amputation on the right foot in April 2010 wound healing was very slow. L-Mesitran Soft application speeded up wound healing not influencing the patient’s glycaemic levels and no adverse events were reported or antibiotics used. Honey-based products can play a vital role in the management of diabetic foot ulcers.

This case study was published in the Wounds UK Journal and you can click here to read the complete story.

The authors of this publication are Natércia Candeias, endocrinologist, and Manuel Cardoso, RN, from the CLINAVIT clinic in Lisbon, Portugal.

Please do not hesitate to contact us, should you have any questions regarding the presented case study.

Manejo de úlcera de pie diabético con el uso de miel

La última publicación de la revista Wounds UK Journal presentó un estudio de caso sobre el uso de L-Mesitran Soft en el tratamiento de úlceras de pie diabético.

Un paciente masculino de 48 años de edad, con diabetes tipo 1, presentaba neuropatía diabética sensitivo-motora y autonómica. Luego de una amputación en el pie derecho en Abril de 2010, la cicatrización de la herida transcurrió de manera considerablemente lenta. La aplicación de L-Mesitran Soft aceleró la cicatrización de la herida sin alteración de los niveles de glucosa del paciente y no se observaron efectos adversos ni fueron utilizados antibióticos.Los productos a base de miel pueden cumplir un papel vital en el manejo de úlceras de pie diabético.

Este estudio de caso fue publicado en la revista Wounds UK Journal y usted podrá hacer click aquí para leer el caso completo.

Los autores de este estudio de caso son Natércia Candeias, endocrinóloga ; y Manuel Cardoso, RN, de la clínica CLINAVIT en Lisboa, Portugal.

Por favor, no dude en contactarnos si tiene alguna pregunta relacionada con el estudio de caso presentado.

October 6, 2011

Use of honey products in lower limb lymphoedema and recalcitrant wounds

The latest Wounds UK Journal published a case study on the use of L-Mesitran in lower limb lymphoedema and recalcitrant wounds.

Investigators from two different Community Health Centers in Portugal successfully used L-Mesitran to heal recalcitrant ulcers in lymphoedematous lower limbs. The patient was a 45 year old female who also suffered from obesity (BMI=53).

The lesions were present for 8-14 years (!) in which period iodine, antibiotics and other products were used to try to heal the malodorous wounds (they could be smelled throughout the patients home).

In November 2009 swabs showed a Gram negative infection (Proteus mirabilis). The patient was hospitalized and treatment with L-Mesitran Ointment from the onset quickly debrided the infected legs without the use of antibiotics. The wounds healed completely in approximately 3½ months. At the six-month follow-up, the patient remained free of ulcerations.

This case study was published in the Wounds UK Journal and you can click here to read the complete story.

The authors of this case study are Cristina Miguéns, RN, Fernanda Inglês, GP and Antonio Jorge Seco, RN.

Please do not hesitate to contact us, should you have any questions regarding the presented case study.

Uso de productos de miel en linfedema y heridas recalcitrantes de miembros inferiores

La última publicación de la revista Wounds UK Journal presentó un estudio de caso sobre el uso de L-Mesitran en linfedema y heridas recalcitrantes de miembros inferiores.

Investigadores de dos diferentes Centros de Salud en Portugal utilizaron con éxito el producto L-Mesitran para tratar úlceras en miembros inferiores con linfedema. La paciente de 45 años, también padecía de obesidad (IMC=53).

Las lesiones permanecieron por 8-14 años (!), periodo durante el cual yodo, antibióticos y otros productos fueron utilizados para intentar cicatrizar las heridas que presentaban mal olor (este se podía percibir por toda la casa de la paciente).

En Noviembre de 2009, un frotis reveló una infección por organismos Gram negativos (Proteus mirabilis). La paciente fue hospitalizada y el tratamiento con L-Mesitran Ointment desde el inicio desbridó de manera rápida las piernas infectadas sin necesidad del uso de antibióticos. Las heridas cicatrizaron completamente en aproximadamente 3½ meses. Al sexto mes de seguimiento, la paciente permaneció libre de ulceraciones.

Este estudio de caso fue publicado en la revista Wounds UK Journal y usted podrá hacer click aquí para leer el caso completo.

Los autores de este estudio de caso son Cristina Miguéns, RN, Fernanda Inglês, GP y Antonio Jorge Seco, RN.

Por favor, no dude en contactarnos si tiene alguna pregunta relacionada con el estudio de caso presentado.

October 5, 2011

Diabetic foot infection treated with honey based L-Mesitran Soft and Hydro

Today we would like to share another case study about a severely infected diabetic foot. This time however, the wound was treated with L-Mesitran Soft gel and L-Mesitran Hydro dressing.

The left foot of a female (77 years) DM Type 2 showed strong signs of infection and necrosis. The wound was most probably caused by a minor injury which hadn’t been noticed due the loss of sensitivity.

Prior to the honey-treatment, the necrotic tissue was manually removed and a culture swab was taken. The patient received intravenous antibiotics to combat the isolated (Staph. lugdunensis, Streptococcus constellatus ssp pharyngis and Streptococcus constellatus ssp) infection, but unfortunately after one week of this conventional treatment it was necessary to amputate the big toe. The area was too much damaged to salvage.

The post-operative wound was treated with the honey based products. After only 4 days of treatment the exudates decreased significantly and the inflammation disappeared. After 1,5 month the wound was fully healed, without affecting the blood glucose levels.

You can click here to read the complete story.

Please do not hesitate to contact us, should you have questions or remarks about the presented case study. You can also contact us, if you want to contribute to the case study series.

September 19,  2011

EPUAP study: Multiple lesions in a person with scleroderma – Pain reduction with honey gel (PUSH® score)

During the EPUAP 14th annual European Pressure Ulcer Meeting in Oporto (Portugal) dr Rui Carvalho and his team presented an interesting case.

A 60 year old female with scleroderma and severe pulmonary hypertension with three wounds in her right leg. Previous treatments with e.g. alginates, collagen or silicone failed; the treatment was started with L-Mesitran Hydro.

The honey treatment allowed the control of non-viable tissue, the decrease of exudate and the increase of the granulation tissue. However, the most relevant change (measured in PUSH score) was the pain reduction. During the treatment no additional antibiotics were administered and therefore hospitalization was avoided.

You can click here to download the poster.

Please do not hesitate to contact us, should you have any questions regarding the presented poster.

Estudio EPUAP: lesiones múltiples en paciente con esclerodermia - reducción del dolor con gel a base de miel (puntuación PUSH ®)

Durante la 14 edición del EPUAP, Encuentro anual europeo de úlceras por presión en Oporto (Portugal) el Dr. Rui de Carvalho y su equipo presentaron un caso interesante.

Una mujer de 60 años de edad con esclerodermia e hipertensión pulmonar severa, presentaba tres heridas en su pierna derecha. La paciente recibió tratamientos previos, específicamente con alginatos, colágeno y silicona que fueron fallidos; se inició entonces un tratamiento con L-Mesitran Hydro.

El tratamiento con miel permitió el control del tejido no viable, disminuyó la cantidad de exudado y aumentó la formación de tejido granular. Sin embargo, el cambio más relevante (medido en la escala PUSH) fue la reducción del dolor. Durante el tratamiento no se administraron antibióticos adicionales y por lo tanto se evitó la hospitalización.

Puede hacer clic aquí para descargar el poster.

Por favor, no dude en contactarnos si tiene alguna pregunta con respecto al poster presentado.

September 9, 2011

Staph.aureus biofilm on infected diabetic foot treated with honey-based L-Mesitran ointment

For most of us the holiday season is over and we hope that you have enjoyed your holiday. Now it is time again to resume our Newsletter service.

We would like to share one of the case studies done by Dr. Wei-Chao Huang, M.D. Phd. from the Chang Gung Memorial Hospital in Taipei, Taiwan.

A 37 year old male patient was diagnosed with Diabetes Mellitus Type 1.The patient had a wound on his right foot, due to repeated trauma.The wound was previously treated with topical antibiotics, but this treatment was not able to provide adequate debridement and delayed wound healing.

The wound was coated with a biofilm caused by Staph. aureus. After the application of L-Mesitran Ointment the biofilm was removed and thereafter the sloughy tissue was removed in three weeks time.

You can click here to read the complete story.

Please do not hesitate to contact us, should you have any questions regarding the presented case study.

Pie diabético infectado con un Biofilm de Estafilococos aureus tratado con el
gel a base de miel L-Mesitran

Para la mayoría de nosotros la temporada de vacaciones ha terminado y esperamos que usted las haya disfrutado. Ahora es el momento para reanudar nuestro servicio de Newsletter.

Nos gustaría compartir uno de los estudios de caso realizados por el Dr. Wei-Chao Huang, MD, PhD. en el Hospital Chang Gung, en Taipei, Taiwán.

Un paciente de 37 años de edad fue diagnosticado con Diabetes Mellitus Tipo 1.El paciente presentaba una herida en su pie derecho, debido a un trauma repetido. La herida fue previamente tratada con antibióticos tópicos, sin embargo este tratamiento no proporcionó un desbridamiento adecuado y retrasó la cicatrización de la herida. La herida se encontraba cubierta por un biofilm causado por Estafilococos aureus .

Después de la aplicación de L-Mesitran, la película fue retirada y posteriormente el tejido necrótico fue removido en tres semanas.

Puede hacer clic aquí para leer el estudio completo. Por favor, no dude en contactarnos si tiene alguna pregunta relacionada con el estudio de caso presentado.

September 1, 2011

Single blinded, randomized, prospective study: L-Mesitran ointment is effective in the treatment of Pyoderma in dogs

In a Swedish single blinded, randomized, prospective study compared the topical treatment of Pyoderma in dogs with L-Mesitran and conventional treatments. The L-Mesitran honey treatment has proven to be safe, without side effects and easier to perform. The results suggest that L-Mesitran is an effective treatment option compared with shampooing.

Uppsala, Sweden - In February of this year a single blinded, randomized, prospective study about the efficacy of L-Mesitran ointment in the treatment of Pyoderma in dogs, compared to the use of 3% chlorhexidine shampoo was published online.

The purpose of this study was to evaluate whether L-Mesitran was effective for the treatment of surface pyoderma in dogs.

Pyoderma is a very common skin disease in dogs and should always be considered as a secondary infection to an underlying disease. Surface pyoderma is the most superficial and mild form of pyoderma which is usually treated topically with antibacterial shampoo and/or topical antibiotics.

Use of antibiotics induces a risk of bacteria developing resistance, which is an increasing medical problem. L-Mesitran is a honey based CE-marked wound ointment which has in several studies proved to have a good antibacterial effect and does not pose the risk of inducing resistant microorganisms.

The results of this study show that topical treatment with L-Mesitran has an equally good effect on surface pyoderma in the dog compared with 3% chlorhexidine shampoo. The treatment method has proven to be safe, no side effects could be observed and the owners experienced the treatment easier to perform compared with shampooing.The results suggest that L-Mesitran can be an effective treatment option compared with shampooing.

The study was performed by Zandra Jakobsson of the Swedish University of Agriculture, faculty of Veterinary Medicine and Animal Science, department of Clinical Sciences.

The original Swedish version is published online and can be downloaded via: http://stud.epsilon.slu.se/2224/. You can click here for our English translation.

July 11, 2011

Recurrent ulcers in a patient with post-thrombotic syndrome treated with honey

Doctor Pereira Albino (vascular surgeon) wrote a case report titled: “Recurrent ulcers in a patient with post-thrombotic syndrome." This was published in the latest Wounds UK Journal (Vol.7, No.2).

This case study reports about the significant therapeutic advantages of the honey-based dressings (L-Mesitran) over other previously used dressings. The recurring ulcer was successfully healed in six weeks, without any adverse effects and with minimal material costs. Honey dressings showed to be a non-invasive and cost-efficient alternative therapy compared to standard treatment methods, or surgical intervention for leg ulcerations.

You can click here to read the complete article.

Úlceras recurrentes en un paciente con síndrome post-trombótico tratadas con miel

Medico Pereira Albino (cirujano vascular), escribió un caso clínico titulado: "Ulceras recurrentes en un paciente con síndrome post-trombótico" . Este fue publicado en el último Wounds UK Journal.

Este estudio de caso reporto las ventajas terapéuticas significativas de los apósitos a base de miel (L-Mesitran) con respecto a otros apósitos utilizados anteriormente. La úlcera recurrente fue exitosamente cicatrizada en seis semanas, sin efectos adversos y con un mínimo costos de material. Los apósitos de miel demostraron ser una terapia alternativa no invasiva y costo-efectiva en comparación con los métodos de tratamiento estándar o con intervenciones quirúrgicas para ulceras en las piernas.

Puede hacer clic aquí para leer el artículo completo.

July 5, 2011

Clinical evaluation of honey-based products for lower extremity wounds in a home care setting

Filip Kegels (RN) wrote a clinical research/audit article in the new Wounds UK Journal  titled:

“Clinical evaluation of honey-based products for lower extremity wounds in a home care setting.”

In this article the author evaluated the honey-based products (L-Mesitran) in a home care setting over a five-year period. In that time 22 cases of lower extremity wounds were treated with L-Mesitran. All retrospectively selected patients were initially treated with povidone iodine or fusidic acid, which resulted in delayed wound healing. Fifty percent of the wounds were infected. Treatment with L-Mesitran resulted in removal of infection and wound healing.

The results of this evaluation indicate that honey-based products are antibacterial, help to debride the wound and promote wound healing, and are safe and easy to use as well as being cost-effective.

You can click here to read the complete article.

"Evaluación clínica de productos a base de miel para heridas en las extremidades inferiores en un entorno de atención domiciliaria".

Filip Kegels (RN) escribió un artículo de investigación/auditoría clínica en el nuevo Wounds UK Journal titulado:

En este artículo el autor evaluó los productos a base de miel (L-Mesitran) en un entorno de atención domiciliaria durante un período de cinco años. En este tiempo fueron tratados 22 casos de heridas en las extremidades inferiores con L-Mesitran. Todos los pacientes seleccionados retrospectivamente fueron tratados inicialmente con Yodo povidona o ácido fusídico, dando como resultado un atraso en la cicatrización de las heridas. El cincuenta por ciento (50%) de las heridas se infectaron. El tratamiento con L-Mesitran dio como resultó la eliminación de la infección y la cicatrización de las heridas.

Los resultados de esta evaluación indican que los productos a base de miel son antibacterianos, ayudan a desbridar la herida, promueven la cicatrización de las heridas y son seguros y fáciles de usar, además de ser costo–efectivos.

Puedes hacer clic aquí para leer el artículo completo.

July 4th, 2011

Ulcus cruris venosum treated with honey-based L-Mesitran ointment and Soft

A 37 year old Rumanian man developed thrombosis in ’92 and ’93. As this was not treated correctly, his first wounds developed in ’95. In ‘02 his CVI was at stage II. In ‘06 his CVI was at stage III and he had developed a chronic ulcus cruris venosum. In 2009 the patient was presented again and then it became apparent, that after three years the wounds had had little progress.

From then on the wounds were treated with the honey-based L-Mesitran. During the treatment no systemic antibiotics were administered. The wounds improved very slightly and after two years a joined decision was made that the patient was no longer followed up with pictures etc. because it became apparent that this patient had underlying pathology that prevented full wound healing. The only option for full healing might be a surgical intervention.

However, the main advantage the honey based products had for this CVI patient was, that during the treatment no systemic antibiotics were needed to combat and prevent infection. Thus the honey products contributed to the reduction of the use of antibiotics and aiding in preventing antibiotic resistance.

You can click here to read the complete story.

Please do not hesitate to contact us, should you have any questions regarding the presented case study.The case study is also available in Dutch (on demand)

June 20, 2011

Diabetic trauma treated with honey based L-Mesitran Soft

This time we would like to share a case study about a diabetes type 2 (DM2) trauma. When not properly treated, it can deteriorate quickly due to impaired soft tissue regeneration. This is a known complication associated with DM2.

A female DM2 patient, 63 years old, had a wound on her left hand caused by an accident. At first a relatively severe swollen hand and a black necrotic spot was noticeable. This necrotic tissue and the peri-wound area suggested a bacterial burden which was quickly reduced within 5 days with the honey-gel. This reduction in wound size is remarkable, taken into consideration that wound healing in diabetics is usually a very long process that can take months.

The wound fully healed in 20 days. Furthermore no changes in glycaemia levels were recorded during the honey treatment.

You can click here to read the full story.

May 3, 2011

Gangrenous diabetic foot ulcer treated with L-Mesitran ointment

This time we would like to share a case study about the treatment of one of the most devastating conditions: gangrene. In this case study we observed excellent results in treating the diabetic wound with the honey products.

A 50 year male was diagnosed with diabetes mellitus type 2. In 2005 he developed gangrene on the little toe of the (right) foot. This led to amputation of the toe. In 2006 and 2009 he had a recurrence of gangrene which unfortunately led to more amputations.

This time however, the wound was treated post-op with L-Mesitran honey ointment. The Pseudomonas aeruginosa infected wound progressed to full wound healing in 3½ months, without any adverse effects and without influencing the blood glucose levels. Perhaps even more important: at one year follow up, the gangrene ulcers had not returned.

You can click here to read the full story.

Would you like to share your experiences with L-Mesitran too? Please do not hesitate to contact us!

April 18, 2011

The use of honey based L-Mesitran in paediatric burns and other wounds

Ahead of the publication on the website of the Wounds-UK Journal, please find below two abstracts from the latest publications about L-Mesitran use in wound management. (Wounds UK, 2011, Vol 7, No 1.)

  •  Eleftheris Smaropoulos et al. wrote a clinical research/audit article titled: “Honey-based therapy for paediatric burns and dermal trauma compared to standard hospital protocol.”

This article compares the clinical use of L-Mesitran honey-based products for the treatment of paediatric partial-thickness burns and skin lesions with results from cases treated with conventional methods. The honey-based therapy indicates a fast (19 days vs 25–31 days), cost-effective and patient-friendlier treatment method compared to povidone iodine.You can click here to read the complete article.

  • Jackie Stephen-Haynes and Rosie Callaghan wrote a clinical review titled: “Properties of honey: its mode of action and clinical outcomes.”

This article outlines the key actions of honey when used as a treatment for wounds and examines the evidence base for its efficacy and impact on clinical outcomes. The Mesitran range of dressings is described and individual case reports presented which demonstrate the use of these products in clinical practice.You can click here to read the complete article.

Please do not hesitate to contact us, should you have any questions about these articles.

El uso de L-Mesitran, producto a base de miel en quemaduras pediátricas y otras heridas

Después de la publicación en la página web de la revista Wounds-UK,, por favor encuentren a continuación dos resúmenes de las publicaciones más recientes sobre el uso de L-Mesitran en el tratamiento de las heridas. (Wounds UK, 2011, Vol 7, No 1.)

  • Eleftheris Smaropoulos et al. escribió un artículo auditado sobre una investigación clínica titulada: ". Terapia a base de miel para quemaduras pediátricas y traumatismos cutáneos en comparación con el protocolo estándar de un hospital"  

Este artículo compara el uso clínico de L-Mesitran, productos a base de miel en el tratamiento de quemaduras pediátrica de espesor parcial y lesiones de la piel con los resultados de los casos tratados con métodos convencionales. La terapia a base de miel es un tratamiento más rápido (19 días vs 25 a 31 días), costo efectivo, y menos traumático comparado con la Yodopovidona. Puede hacer clic aquí para leer el artículo completo. 

  • Jackie-Stephen Haynes y Callaghan Rosie escribieron una reseña clínica titulada: "Propiedades de la miel: su modo de acción y los resultados clínicos."

En este artículo se describen las acciones principales de la miel cuando se utiliza como tratamiento para heridas y se examina la evidencia de su eficacia y el impacto sobre los resultados clínicos. Se describen la gama de apósitos L-Mesitran y se presentan informes de casos individuales que demuestran el uso de estos productos en la práctica clínica.Puede hacer clic aquí para leer el artículo completo.

Por favor, no dude en contactarnos si tiene alguna pregunta acerca de estos artículos.

April 5, 2011

Cranial wound after removal of basal epithelioma - treated with L-Mesitran honey ointment

Today we would like to share a case study which shows  L-Mesitran's excellent capability to debride sloughy, malodorous and necrotic wounds quickly.

A 70 year old woman showed basal cell epithelioma on top of her head. In this case surgery was performed to remove the malignant epithelioma and perform a partial convergence of the wound, resulting in a wound of ± 8cm x 4.6cm and 0.5cm deep.

Initially the wound was treated with povidone iodine 10% solution and fusidic acid paraffin gauze, but necrotic tissue developed, combined with high exudates and malodour.

Then the switch to L-Mesitran honey Ointment & Net was made. The progress was remarkable and within 8 days the malodour was gone and granulation observed, leading to full wound healing in two months.

You can click here to read the full story.

Please do not hesitate to contact us should you have any questions about the presented case study or if you want to contribute to the case-study series.

March 21, 2011

Trauma wound on distal equine limb - treated with honey based L-Mesitran

This time we would like to underline L-Mesitran's effectiveness in the treatment of difficult distal equine limb wounds, even if wounds are left to heal per secundam.

Distal equine limb wounds are of concern due to loss of performance and potential loss of commercial value, since they have a longer healing time than wounds of the trunk.

In this case a 19 year old mare fell and hurt herself severely at the back of her right leg.The wound healed completely within 4,5 months and the use of honey ointment has clearly accelerated wound healing.

You can click here to read the full story.

Please do not hesitate to contact us, should you have any questions about the presented case or if you want to contribute to our case study series.

February 23, 2011

Proteus contaminated chronic ulcus cruris (UCV) treated with L-Mesitran Ointment and Net

Today we would like to underline L-Mesitran's capability to debride wounds, reduce bacterial burden and start granulation.

In this case  study, a 65 year old woman presented a Gram negative (Proteus)contaminated Ulcus Cruris Venosum (UCV). In case of a contaminated UCV, woundbed preparation is crucial to facilitate ordered restoration and regenerating of damaged tissue. The Gram negative contamination prevented healing and antibiotics were remarkably not able to control the infection and even delayed wound healing.

The honey therapy however, quickly reduced the bacterial burden and allowed the wound to heal in roughly 4 months.

You can click here to read the complete story.

Please do not hestitate to contact us, should you have any questions or remarks about the presented case study and feel free to share your story too!

February 7, 2011

2011 International Equine Congress for Veterinarians: Acute Wound Healing With Honey

A KWPN mare (21) presented a large wound on the tarsus (left rear leg). The wound was caused by housing facilities. Due to neglect, the wound could only heal by secondary intention. The wound was debrided by autolysis and the infection reduced without use of antibiotics, but with the honey-based L-Mesitran.

Click here to take a look at the poster which will be presented during the International Equine Congress for Veterinarians which will take place on January 22nd and 23rd in Brussels..

The poster presentation will be done by Alex Brander (RN) who has been a registered nurse for 25 years and recently has dedicated his career to veterinary wound care. www.veterinairewondzorg.nl.

Click on the following link for more information about the Equine Congress in Brussels: http://www.hipposcongress.eu/start.php?lang=en.

Should you have any questions regarding the veterinary use of L-Mesitran, please do not hesitate to contact us.

January 17, 2011

First new publication about L-Mesitran of 2011! The salvage of an MRSA-infected titanium mesh in a large incisional ventral hernia

The year has started very promising with a publication regarding the use of L-Mesitran in The World Journal of Hernia and Abdominal Wall Surgery (‘Hernia’).

The article by Dr Chatzoulis et al. reports a case report and literature review on the salvage of an MRSA-infected titanium mesh in a large incisional ventral hernia.

This was done using a novel technique; a combination of VAC-therapy and L-Mesitran Ointment.This combination proved to be successful in leaving the mesh in situ, an important achievement, because serious complications are reported following mesh removal.

The article also reviews the literature regarding the possible pathogenetic mechanisms and treatment options. An abstract of this article can be found via http://www.ncbi.nlm.nih.gov/pubmed/21191626

El año ha empezado de una manera prometedora con la publicación de un artículo sobre el uso de L-Mesitran en The World Journal of Hernia and Abdominal Wall Surgery (‘Hernia’).

El artículo de Dr. Chatzoulis et al. describe un estudio de caso y revisión de la literatura en un salvamento de una malla de titanio con infección por MRSA en una gran hernia incisional ventral.

Esto se realizó mediante una técnica innovadora: la combinación de la terapia VAC con el ungüento L-Mesitran. Esta combinación demostró ser exitosa dejando la malla in situ, un logro importante, debido a las complicaciones graves que se describen tras la retirada de la malla.

El artículo también revisa la literatura sobre los posibles mecanismos patogénicos y opciones de tratamiento. Un resumen de este artículo se puede encontrar en http://www.ncbi.nlm.nih.gov/pubmed/21191626

January 10, 2011

 

 

 

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